OH! NO! SAY IT AINT SO! NO MORE TWINKIES!

And you thought the gas shortage was bad.

There was a desperate run on Twinkies after Hostess announced Friday it’s going out of business amid bankruptcy and labor strife.

The company’s outlet in Queens was stripped bare of the creme-filled golden sponge cake and snacks like Sno Balls, Ding Dongs, Devil Dogs and Ho Ho’s.

Boxes of Twinkies were being hawked on eBay for thousands of dollars, and New Yorkers were facing a future without Drake’s cake or Wonder Bread.

“We just spent $100 on Twinkies,” said Shauna Miles, 33. “Tomorrow we’re gonna wake up with diabetes.”

She chuckled at the sight of sugar addicts stocking up.

“First everybody was going crazy over gas. Now we’re losing our minds over cupcakes,” Miles said.

Hostess may sell some of the most popular brands and recipes, but that won’t help 18,500 workers getting the ax.

“It’s a lot of people out of a job at the wrong time. Christmas is coming,” said Deomarin Dhanna, who works at the outlet store in Jamaica.

Even though it racks up $2.5 billion in sales a year, Hostess is in bankruptcy for the second time in a decade.

The company wanted to slash worker wages and benefits, and while the Teamsters struck a deal, the bakers union balked and went on strike last week. The company vowed to shut its 33 plants if workers weren’t back on the job by Friday.

“We deeply regret the necessity of today’s decision, but we do not have the financial resources to weather an extended nationwide strike," said CEO Gregory Rayburn, who headed up NYC OTB when it shut down.

The Teamsters said the company was mismanaged but slammed the bakers union for not compromising. The bakers had no comment.

The bottom line also may have been hurt by competition and anti-junkfood campaigns.

“They didn’t change with the times,” said Ivan Arguello, owner of a Key Food in Brooklyn Heights. “My children don’t even know what Drake and Hostess are.”

But Lorraine Bennett, 53, of Bedford-Stuyvesant, Brooklyn, was outraged by the news.

“Twinkies are my favorite! I love that cream filling. And you can fry them. We’ve got to protest,” she said.

Bennett may not have fried her last Twinkie.

“I would be surprised if the brands themselves don't survive,” said Cathy Hershcopf, a bankruptcy partner at Cooley LLP. “They are iconic and someone's going to step up and buy them.”

Look @ this fool right hereHe's serious too!

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