A major disturbance at Rikers Island Saturday night sent 12 correction officers and three inmates to the hospital.
Authorities said several inmates refused to go to their cells for routine lock-in, ABC Eyewitness News reported.
Prison officials said the melee may have been sparked by anger over a prisoner search earlier in the day.
The jail was put on heightened alert Sunday.
The injured inmates are awaiting trial and were identified as high-security prisoners.
Most injuries were minor, but one officer required 20 stitches for gashes on his head and face.
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