A Yale University medical team is touting ketamine - a.k.a. the recreational drug Special K - as the latest miracle drug for the treatment of severe depression.
In studies with rats, scientists that the drug improves mood and seems to restore connections between brain cells damaged by chronic stress, according to a recent issue of the journal Science.
"It's like a magic drug - one dose can work rapidly and last for seven to 10 days," Ronald Duman, professor of psychiatry and pharmacology at Yale and senior author of the study told the journal.
Even in low doses, the drug, once used as a general anesthetic for children, was seemed to give patients relief from depression, Duman said. However, its clinical use has been limited because it has to be delivered intravenously due to the possibility of cause short-term psychotic symptoms.
These study findings could speed development of an easy-to-administer version of the drug to treat severely depressed patients, reports the Journal.
Ketamine is best known for its illegal, recreational abuse. In the 1990s, 'Special K' or 'K' along with Ecstasy, was a popular rave drug.
At lower doses, users are likely to experience a mild, dreamy feeling similar to nitrous oxide, according to DanceSafe.com. Higher doses produce a hallucinogenic, out-of-body effect.
The drug, taken at too high a dosage or without medical supervision, can cause psychotic effects, as well as depressed breathing and heart rate and addiction.
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