GAME OVER! SHAQ'S WIFE FILES FOR A SEPARATION!

The clock's run out on Shaquille O'Neal's marriage.
According to court papers, wife Va'shaundya "Shaunie" O'Neal filed for legal separation from the Cleveland Cavaliers player in Los Angeles County Superior Court on Monday, TMZ.com reports.

She cites irreconcilable differences for the demise of her seven-year marriage to the 37-year-old athlete.

In addition to asking for an unspecified amount of money for spousal and child support, Shaunie is also seeking sole custody of the couple's four minor children, ages 3 to 9, with visitation rights for O'Neal.

Though the couple lives in Florida, Shaunie claimed she's a resident of California, which has more generous community property divorce provisions.

According to People.com, Shaunie recently flew to Los Angeles and claimed herself a resident of The Golden State on Nov. 8, one day before filing the separation papers.

This is the second split for Shaunie and Shaq, who originally filed for divorce in 2007.

The couple, who reportedly have a prenuptial agreement, eventually reconciled after a bitter dispute over whether or not he was hiding money from her.