The iconic singer was up for a whopping 11 awards — the most she's ever been nominated for and the highest number of nods any artist received at this year's ceremony.
She nabbed the highly coveted Video of the Year award for "Formation," thanking her "beautiful daughter and incredible husband for all their support."
She dedicated the honor to the people of New Orleans, who are reeling from catastrophic damage following deadly flooding in Baton Rouge, La.
Earlier in the night, the "Halo" hit maker also won Female Video of the Year for "Hold Up."
Here is a list of all the winners:
Video of the Year
Best Female Video
“Hold Up,” Beyoncé
Best Male Video
“This Is What You Came For,” Calvin Harris ft. Rihanna
“Work From Home,” Fifth Harmony ft. Ty Dolla $ign
Best Hip Hop Video
“Hotline Bling,” Drake
Best Pop Video
Best New Artist
Song of Summer
“All in My Head,” Fifth Harmony featuring Fetty Wap
Best Rock Video
“Heathens,” Twenty One Pilots
Best Electronic Video
“How Deep Is Your Love,” Calvin Harris & Disciples
Breakthrough Long Form Video
Video Vanguard Award
Best Art Direction:
“Blackstar,” David Bowie
Best Visual Effects: